Polkadot Poison Dart Frog (Oophaga arborea: Dendrobatidae) These small frogs are 2.0-2.2 cm (0.79-0.87 in) long. They are highly toxic, containing many alkaloids that cause breathing difficulty, locomotor problems, and eventual death (Myers et al.1984). Photographed on Ancon Hill, Panama Province, Panama City, Panama. Lowland tropical rain forest about half way up Ancon Hill at ca. 107 m (350 ft) elevation.